Maffucci Syndrome and Ollier's Disease DefinitionsMaffucci Syndrome and Olliers Disease Definitions page Photo


The following have been defined by a variety of sources.

These will be kept updated as much as possible to ensure accurate information and guidance is available.

Please use our online mail form on the 'Contact us' page to provide any information you have found useful to help others and their understanding of these conditions. 


What does that mean ...


What is an Enchondroma?

  • Type of benign bone tumour that originates from cartilage.
  • Exact origination of the tumours are not known.
  • As you grow cartilage turns to bone, during this process the cartilage ‘forgets’ and stays as it is.
  • Most often affects the cartilage that lines the inside of the bones.
  • The bones most often affected with this benign tumour are the miniature long bones of the hands and feet. It may, also involve other bones such as the humerus, tibia or femur.

 What is a Hemangioma?

  • Most common type of birthmark
  • It is a benign (non cancerous) tumour of the cells. These are called endothelial cells (the cells that line the blood vessels)
  • Usually found on the surface of the skin – a collection of small blood vessels in or under the skin, they can be superficial or deep.
  • They can be red in colour or have a bluish tinge.


What is Ollier's Disease?

  • A rare non-hereditary bone disorder
  • Ollier’s Disease can also be called enchondromatosis
  • Ollier’s Disease is the findings of multiple enchondromas
  • Echondromas can be found anywhere in the body
  • Non-heridatary condition

Ollier’s Disease can affect anybody male or female Ollier’s disease is a rare nonhereditary sporadic disorder where intraosseous benign cartilaginous tumors develop close to growth plate cartilage. Prevalence is estimated at around 1 in 100,000.

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What is Maffucci Syndrome?

  • A rare non-hereditary bone disorder
  • Maffucci Syndrome as Olliers Disease is the finding of multiple enchondromas but also soft-tissue haemangiomas (showing as a bluish nodule or dark red irregular patches)
  • Echondromas and Haemangiomas can be found anywhere in the body
  • Non-heridatary condition

Maffucci Syndrome Maffucci syndrome is a sporadic disease characterized by the presence of multiple enchondromas associated with multiple hemangiomas. Also lymphangiomas may be apparent.

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What are the Signs and Symptoms of these conditions?

       Each individuals case is and can be diagnosed and develop differently.

  • A lump or swelling that makes the bone look an odd shape
  • Aching pain that doesn’t disappear
  • Bone with alot of cartilage can grow slower, causing bones to look bent or crooked
  • Can fracture the bone as the cartilage weakens the area
  • Maffucci Syndrome – Haemangioma, these may be superficial or deep, soft bluish bumps or dark red irregular patches
  • Chance of malignancy


What is the Treatment for these conditions?

  • Regular monitoring and physical examinations to evaluate changes in enchondromas and haemangiomas
  • Each individual is different and will depend on symptoms – x-rays and/or scans will show in more detail
  • Surgery is available for lengthening of limbs or removal of tumours
  • As there is no medical protocol for these conditions, there is no set procedure. Visit ‘Share your story’ and ‘Forum’ for more information on this area, each inidividual is different and sharing information which can be passed onto our individual medical professionals to ensure the most suitable treatment is provided for each case.


Useful Links


These links provide useful information and guidance on Maffucci Syndrome and Ollier's Disease and help with the understanding of the condition.